I’m a diehard Bills fan to start off. So take anything I write with that Bias. But here is objective I can be about the match-up
Jets offense vs Bills defense
Jets May have improved their talent level on the line, but continuity is biggest factor in good line play. No offseason, no preseason will hurt the Jets in this game. Can see limited holes for Bell, Gore and Perine. Honestly I think Bell is done, the Bills know and respect Gore but he is old and slow. Perine is still dinged up with ankle. I can’t see Darnold being able to get anything going in the deep and intermediate passing game. Take the Jets lack of receiving talent, the Bulls superior secondary play force the Jets to base their passing offense to short throws to Crowder and Herndon. To me that is not the pathway for a successful sustained offense. Unless the Jets can get short field opportunities I don’t see them able to sustain drives and generate points.
Bills Offense Vs Jets defense
Have a lot of respect for Jets defensive line and feel this may be an advantage against Bills offensive line. But the lack of pass rush and poor corner play leave them open to a wide and diverse passing attack by Buffalo, Diggs, Brown, Beasley outmatch anything the Jets have at corner. I like your three safeties but your line backing is weak and even if your dline gets pressure can they really contain Allen on scrambles and broken plays. If Grego does his big blitz scheme your corners won’t be able to hold up and will probably get scorched. The only chance the Jets have is Singletary having ball security issues or bad Josh showing up. Honestly to be in the game the Jets would need to be +3 in turnover differential
Special Teams - With rookie Tyler Bass forget about any kickoff returns, every ball is going thru the end zone. Bills special teams have excellent gunners in Neal and Jones, great punt returner in Andre Roberts (you remember him I think) and are only marginally weak at our punter. But he kicks high and can be lace the ball fairly well.
Coaching Match-up - Adam Gase, is their anything else that needs to be written.
My biased prediction is Bills 34 Jets 10, Bills get up 24-3 at half, coast in 2nd, give up late who cares TD against Bills back-ups